Teachers in the Department of Classical Languages and Literatures are also researchers, specializing in a wide range of fields: Egyptology, Greek economic history, Latin and neo-Latin literature, ideology of power in Rome, Greek and Roman numismatics, reception of antiquity... They carry out their scientific activities mainly within the framework of the research centerFontes Antiquitatis, integrated into the PaTHs Institute.

Department members are also involved in the management of the Société des Études classiques, which publishes the revue scientifiqueLes Études classiques, distributed by Peeters. This journal, founded in 1932, publishes works devoted to Greek and Latin languages and literatures and to the sciences of antiquity each year. The journal doubles as a collection of monographs, the "Collection d'Études classiques ".