Upon completion of this course, students will have gained the theoretical bases of pharmacogenetics and will have become aware of the importance of genetic variation in the clinical response to drug treatments.
This course aims to present the basic concepts of pharmacogenetics, from which students will be able to understand the impact of the genome variation in the clinical response to treatments. Numerous examples of current practice will then be discussed, taking from pharmacokinetics and pharmacodynamics, the lack of efficacy and undesired effects, according to the discussed cases. Students will be asked to reflect about the best use of pharmacogenetics assays from the biomedical and the medical point of views, and to include these approaches in the personalized medicine context and its ethical aspects.
Prof. Gillet:
Prof. Flamion:
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Students, by group of two, present an analysis of a research article.
PowerPoint presentations, textbook of practicals, research and review articles.