Notions of molecular genetics, for students at the second year of pharmacy, having acquired notions of organic Chemistry and Biology.
Provide the basic principles of genetic engineering and genomics, to allow the future pharmacists to understand the new therapeutic approaches resulting from the control of molecular genetics and genomics.
The course contents are divided in four main parts.
- DNA structure : DNA and chromatin, DNA in flux (recombinations, transpositions, ...) and horizontal gene transfer
- DNA functions : gene expression mechanisms
- Genetic engineering : basic principles in molecular biology, DNA sequencing, recombinant protein producrion and the genetic approaches (mutagenesis and transgenesis)
- Human genetic polymorphism and pharmacogenomics
1. Structure of the genetic information
2. Fonctions of the genetic information
3. Genetic engineering
4. Genetic polymorphism
The evaluation is a written exam with multiple choice questions. Questions will not have the same weight for the computing of the final note, but the relative weight of each question is indicated.