Résultats de recherche

Abstract Radiotherapy is a cornerstone of cancer treatment and is currently administered to approximately half of all cancer patients. However, the cytotoxic effects of ionizing radiation on normal tissues represent a major limitation, as they restrict the dose that can be safely delivered to patients and, consequently, reduce the likelihood of effective tumor control. In this context, delivering radiation at ultra-high dose rates (UHDR, > 40 Gy/s) is gaining increasing attention due to its potential to spare healthy tissues surrounding the tumor and to prevent radiation-induced side effects, as compared to conventional dose rates (CONV, on the order of Gy/min).The mechanism underlying this protective effect—termed the FLASH effect—remains elusive, driving intensive research to elucidate the biological processes triggered by this type of irradiation.In vitro models offer a valuable tool to support this research, allowing for the efficient screening of various beam parameters and biological responses in a time- and cost-effective manner. In this study, multicellular tumor spheroids and normal cells were exposed to proton irradiation at UHDR to evaluate its effectiveness in controlling tumor growth and its cytotoxic impact on healthy tissues, respectively.We report that UHDR and CONV irradiation induced a comparable growth delay in 3D tumor spheroids, suggesting similar efficacy in tumor control. In normal cells, both dose rates induced similar levels of senescence; however, UHDR irradiation led to lower apoptosis induction at clinically relevant doses and early time points post-irradiation.Taken together, these findings further highlight the potential of UHDR irradiation to modulate the response of normal tissues while maintaining comparable tumor control.JuryProf. Thomas BALLIGAND (UNamur), PrésidentProf. Stéphane LUCAS (UNamur), SecrétaireProf. Carine MICHIELS (UNamur)Dr Sébastien PENNINCKX (Hôpital Universitaire de Bruxelles)Prof. Cristian FERNANDEZ (Université de Bern)Dr Rudi LABARBE (IBA)

La deadline d'inscription et de soumission pour les abstracts : 20 août 2025.  Plus d'infos sur le site internet de l'Institut NARILIS

This event will be the perfect opportunity not only to discover the latest advances in the field of biological macromolecules research, but also to share knowledge, collaborate, as well as to showcase the outstanding work of PhD students. PhD students are encouraged to submit an abstract for an oral presentation and/or poster. Five talks will be selected on the basis of received abstracts and added to the final programme. Prizes will be awarded for the best oral presentation and the best poster at the end of the event.  More info about abstract submission and registration on the website

L’espace est devenu le lieu d’importants enjeux économiques et stratégiques. Membre de l’Alliance européenne UNIVERSEH, l’UNamur explore cette thématique spatiale dans ses différents départements, de la physique à la géologie, en passant par les mathématiques, l’informatique ou la philosophie. Sans oublier de s’adresser au grand public, que les étoiles font toujours rêver...

Une délégation de l’Université de Namur a participé à une mission exploratoire à l’Université Cheikh Anta Diop (UCAD) de Dakar, au Sénégal. L’objectif : découvrir les recherches menées sur le terrain, rencontrer les chercheurs de l’UCAD et initier de futures collaborations entre les deux institutions. 

Le 15 mars 2023, les Professeurs Henri-François Renard et Alison Forrester ont présenté à un large public d'utilisateurs les nouveaux outils avancés de bio-imagerie disponibles à la plateforme Morphologie et Imagerie (MORPH-IM) de l'UNamur.