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Abstract Radiotherapy is a cornerstone of cancer treatment and is currently administered to approximately half of all cancer patients. However, the cytotoxic effects of ionizing radiation on normal tissues represent a major limitation, as they restrict the dose that can be safely delivered to patients and, consequently, reduce the likelihood of effective tumor control. In this context, delivering radiation at ultra-high dose rates (UHDR, > 40 Gy/s) is gaining increasing attention due to its potential to spare healthy tissues surrounding the tumor and to prevent radiation-induced side effects, as compared to conventional dose rates (CONV, on the order of Gy/min).The mechanism underlying this protective effect-termed the FLASH effect-remains elusive, driving intensive research to elucidate the biological processes triggered by this type of irradiation.In vitro models offer a valuable tool to support this research, allowing for the efficient screening of various beam parameters and biological responses in a time- and cost-effective manner. In this study, multicellular tumor spheroids and normal cells were exposed to proton irradiation at UHDR to evaluate its efficacy in controlling tumor growth and its cytotoxic impact on healthy tissues, respectively.We report that UHDR and CONV irradiation induced a comparable growth delay in 3D tumor spheroids, suggesting similar efficacy in tumor control. In normal cells, both dose rates induced similar levels of senescence; however, UHDR irradiation led to lower apoptosis induction at clinically relevant doses and early time points post-irradiation.Taken together, these findings further highlight the potential of UHDR irradiation to modulate the response of normal tissues while maintaining comparable tumor control.JuryProf. Thomas BALLIGAND (UNamur), PresidentProf. Stéphane LUCAS (UNamur), SecretaryProf. Carine MICHIELS (UNamur)Dr Sébastien PENNINCKX (Hôpital Universitaire de Bruxelles)Prof. Cristian FERNANDEZ (University of Bern)Dr Rudi LABARBE (IBA)

Five years after its inauguration, the Astronomical Observatory of the University of Namur has been enriched by a new set of instruments unique in Belgium: a Schmidt astrograph of the Rowe-Ackermann type, 28 cm in diameter, equipped with a 62-megapixel full-format color camera. These exceptional instruments will offer the public an immersive educational experience unrivalled in the Walloon Region.

Professor Eli Thoré and Justine Bélik have just been honoured by the Adrien Bauchau Fund (FAB). Created in memory of the founder of the Biology Department at UNamur, the FAB has been promoting excellence in education and research in the life sciences since 1989.

An unusual piece of research recently mobilized teams from UNamur's Biology Department. Genetic analyses carried out by the Environmental and Evolutionary Biology Research Unit (URBE) were able to confirm the protected status of a herd of wild mouflons based in Gesves, and thus highlight the importance of saving them.

In May 2025, the Department of Physics welcomed two special visitors: Serge Mathot and François Briard from Namur, both alumni of UNamur and members of CERN. Several activities were on the program, ranging from a visit to the particle accelerator, to science popularization and thematic seminars, particularly in heritage sciences. The aim? To identify areas or activities in which UNamur and CERN could strengthen their collaboration.

We do theoretical and numerical physics. We specialize in photonics, the quantum science of light. We are in the era of the second quantum revolution. There is a craze for a better understanding of light-matter interactions from a fundamental point of view in order to cope with the next generation of quantum devices. This is where our adventure begins. Our tools are theoretical physics, including analytical modeling and numerical simulations, as close as possible to experiments. The group is also developing research activities in the science of teaching and learning, as well as scientific outreach.

The research team is led by Principal Investigator (PI) Professor Michaël Lobet, Qualified Researcher FNRS, who is a member of the Department of Physics, and is also affiliated with the NISM (Pôle de recherche NOP). It is made up of post-doctoral researchers, PhD students and Master's students, whose composition varies from year to year and depending on the project.It aims to be as diverse and inclusive as possible. It is also very proud of its alumni network, which has grown over time and contributed greatly to the team's development. Dedicated to excellence, the research team has been the recipient of numerous prizes and awards.