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Abstract Estrogens originating from human and animal excretion, as well as from anthropogenic sources such as cosmetics, plastics, pesticides, detergents, and pharmaceuticals, are among the most concerning endocrine-disrupting compounds in aquatic environments due to their potent estrogenic activity. While their effects on fish reproduction are well documented, their impact on development, particularly metamorphosis, remains poorly studied. This hormonal transition, mainly controlled by the thyroid axis, is essential for the shift from the larval to the juvenile stage in teleosts.The effects of two contraceptive estrogens on zebrafish (Danio rerio) metamorphosis were evaluated: 17α-ethinylestradiol (EE2), a synthetic reference estrogen, and estetrol (E4), a natural estrogen recently introduced in a new combined oral contraceptive formulation. Continuous exposure from fertilization to the end of metamorphosis allowed the assessment of morphological changes, disruptions of the thyroid axis, and modifications of additional molecular pathways potentially involved in metamorphic regulation.EE2 induced significant delays and disturbances in metamorphosis, affecting both internal and external morphological traits, confirming its role as an endocrine disruptor of concern. In contrast, E4 did not cause any detectable morphological alterations even at concentrations far exceeding those expected in the environment, indicating a limited ecotoxicological risk. Molecular analyses showed that EE2 strongly affected thyroid signaling and energy metabolism during metamorphosis, whereas E4 induced only minor transcriptional and proteomic changes.This study provides the first evidence that EE2 can disrupt zebrafish metamorphosis and highlights the importance of including this developmental stage in ecotoxicological assessments. The results also suggest a larger environmental safety margin for E4, although further research is needed to clarify the mechanisms linking estrogen exposure to metamorphic regulation.JuryProf. Frederik DE LAENDER (UNamur), PresidentProf. Patrick KESTEMONT (UNamur), SecretaryDr. Sébastien BAEKELANDT (UNamur)Dr. Valérie CORNET (UNamur)Prof. Jean-Baptiste FINI (Muséum National d'Histoire Naturelle, Paris)Dr. Marc MULLER (ULiège)Prof. Veerle DARRAS (KULeuven)

On the occasion of the International Day of Women and Girls in Science proclaimed on February 11 by the United Nations General Assembly, and as part of the European alliance European Space University for Earth and Humanity (UNIVERSEH) focusing on the theme of space, discover the testimonies of four women scientists from UNamur working on astronomical themes.

In an ever-changing world, where health, environmental and societal crises are intertwined, it is becoming imperative to rethink health in a global and interconnected approach. It was against this backdrop that the Faculty of Medicine at the University of Namur inaugurated its new "One Health" teaching unit (UE) on Thursday February 06, 2025, in the presence of Minister Yves Coppieters. This initiative, offered to all UNamur undergraduates, aims to train tomorrow's healthcare professionals in a systemic vision, where human, animal and environmental health are considered as one and the same reality.

Helping us to age independently and in good health. This is the aim of Charlotte Beaudart's research into sarcopenia, an age-related disease that can occur as early as the age of 50. The work of the UNamur researcher and member of the Narilis Institute has been rewarded once again, as she has just been awarded the title of "Namuroise of the Year", for the Sciences category!

Founded some 50 years ago, the Laboratoire d'Analyse par Réactions Nucléaires (LARN) in the Department of Physics at the University of Namur is home to a 2MV tandem particle gas pedal named ALTAÏS (Accélérateur Linéaire Tandetron pour l'Analyse et l'Implantation des Solides), in operation since 1999.

The IPCC warns of the growing impact of global warming on water, with more frequent droughts and floods threatening global supplies. By 2050, 42% of river basins will be severely affected, and flood damage could quadruple in the event of 4°C warming. Although they bear little responsibility, the most vulnerable populations suffer the worst consequences. In Wallonia, recent climatic disasters and water pollution illustrate the stakes. To raise public awareness, an event is being organized in Charleroi with debates and screenings.Program17:00 | Introductory session Head of UNESCO Belgium Mr Aurélien Dumont, Secretariat of UNESCO's Intergovernmental Hydrological Programme, World Water Situation17:40 | Screening of the film "H2O, water, life and us: the Emergency"18:30 | Break18:45 | Lectures and debate Prof. Dr. Marnik Vanclooster (U.K.). Marnik Vanclooster (UCLouvain), "Situation en Wallonnie" Prof. Alfred Bernard (UCLouvain), "Normes et toxicologie" Debate Moderated by Prof. Karim ZouaouiBouin (UCLouvain). Karim ZouaouiBoudjeltia (ULB), with the participation of Aurélien Dumont, Marnik Vanclooster, Alfred Bernard.20:30 | Cocktail dinnerGRATULAR : Registration required: f.amer@wbi.beThe members of the "exact and natural sciences" Sub-CommissionBernard Feltz (UCLouvain, Chairman), Bertrand Hespel (UNamur), Marie-Geneviève Pinsart (ULB, CIGB), René Rezsohazy (UCLouvain), Frédéric Rychter (Secrétaire général), Olivier Sartenaer (UNamur), Didier Serteyn (ULiège), Anne Staquet (UMons), Marnik Vanclooster (UCLouvain), Karim Zouaoui Boudjeltia (ULB)

Thomas Balligand, now a lecturer at UNamur, combines his passion for basic research with teaching in histology and cytology. After a diverse background in internal medicine and research, notably at Harvard, he is dedicated to training the next generation of scientists while pursuing his work on nanobodies and their potential in immunotherapy. His desire to awaken scientific curiosity in his students illuminates his new role at the university..

A major breakthrough for the health of women on oral contraceptives has been achieved by researchers in Namur. Every year in Europe, more than 22,000 cases of venous thrombosis or embolism occur among contraceptive pill users. A team of researchers from the University of Namur, in collaboration with QUALIblood (spin-off), has conducted an important study, the results of which could transform prescribing recommendations..

Bringing a new drug to market, particularly when it is intended to treat a pediatric or orphan disease, is a journey fraught with pitfalls. The ERAMET project, coordinated by Professor Flora Musuamba Tshinanu, aims to overhaul the assessment procedures, so that regulatory agencies can take innovative technologies into account and thus make more informed choices.

What is "care"? What is health? This opening conference will be an opportunity to explore the contemporary challenges linked to health, care and the transformations needed for a sustainable, inclusive future.Speakers:Barbara Stiegler, philosopher at Bordeaux-Montaigne UniversityGaël Giraud sj, economist and theologian, researcher at CNRS and Doctor Honoris Causa of UNamurFree conference as part of the partnershipRegistration required. Please make sure you select the February 20 conference. I reserve my place Find out more about the Chair's conferences

Constitutionalism, understood as a means of establishing a political autonomous from society, is seen as having constructed the opposition between the State and society. At the same time, the concept of constitutionalism is increasingly being used to describe other forms of social power and normativity – such as the economy, finance, digital, technologies, media, environment – even though the concrete and theoretical implications of these shifts have not always been fully clarified. More recent trends have emerged within the framework of socio-constitutionalism or societal constitutionalism to challenge the reduction of constitutional issues to state-individual relations, acknowledging the complexity of power. Despite their heterogeneity in assumptions, as well as in their descriptive, normative, and theoretical dimensions, these approaches have contributed to renewing the inquiry into the relationship between constitution and society. The purpose of the conference is to assess the current boundaries of constitutionalism and to explore theoretical proposals seeking to overcome them. These approaches raise several fundamental questions: What role should be granted to social actors and sectors within constitutionalism? How can their normative autonomy be acknowledged while also regulating their private power and expansionist tendencies? To what extent do these transformations challenge traditional forms of politics? At what cost might the relationship between constitution and society be reconsidered today?  Program January 299:00 a.m. Welcome9:30-10:00 Introduction: Manon Altwegg-Boussac (Paris-Est Creteil University/IUF) and Sabina Tortorella (MSCA/University of Namur)From State to Society: New Challenges for ConstitutionalismChair: Isabelle Aubert (Paris Panthéon-Sorbonne University)10:00-10:30 Thomas Boccon-Gibod (Grenoble Alpes University): Relationships between Constitution and Society10:30-11:00 Simone Mao Zhenting (Harvard University): Constitutionalizing Society in an Age of Fragmented Authority: From State-Centrism to Social Constitutional Norms11:00-11:30 Discussion11:30-12:00 Coffee Break12:00-12:30 Angelo Jr Golia (Luiss Guido Carli): Societal Constitutionalism and General Theory of Law (beyond the State): Norm, Order, Interpretation12:30-12:45 Discussion12:45-14:30 LunchMoving Beyond the Nation-State: Theoretical PerspectivesChair: Eleonora Bottini (Sciences Po)2:30-3:00 p.m. Jean-François Kervégan (Paris Panthéon-Sorbonne University): Politics below and beyond the State: Schmitt and Kojève in Comparative Perspective3:00-3:30 p.m. Paul Linden-Retek (University at Buffalo School of Law): Postnational Society and its Law3:30-4:00 Discussion4:00-4:30 p.m. Coffee BreakNew Conceptual Tools: Alterity and DerogationChair: Eleonora Bottini (Sciences Po)4:30-5:00 p.m. Horatia Muir Watt (Sciences Po): On the Borderline (and beyond the State): Ontologizing Alterity on the Terms of the Law5:00-5:30 p.m. Raffaele Bifulco (Luiss Guido Carli): Derogation as Legal Response to Social Differentiation5:30-6:00 p.m. Discussion6:00 p.m. DinnerJanuary 309:00 a.m. WelcomeMapping Sectoral Constitutions: Case StudiesChair: Sabina Tortorella (MSCA/University of Namur)9:30-10:00 Francesco Martucci (Panthéon-Assas University): Trust and Distrust. State, Society, and Money in the Digital Era10:00-10:30 Nefeli Lefkopoulou (Sciences Po): Exploring Constitutional Narratives in Meta’s Oversight Board: Replicating or Renewing Traditional Constitutionalism?10:30-11:00 Discussion11:00-11:30 Coffee Break11:30-12:00 Manuela Niehaus (University of Administrative Sciences Speyer): Global Climate Constitutionalism beyond the State?12:00-12:30 Mathilde Laporte (Pau University): The Debated Protection of Constitutional Rights within Social Orders beyond the State. The Example of Gated Communities12:30-1:00 p.m. Discussion1:00-2:30 p.m. LunchCritical Insights: Take the Leap?Chair: Manon Altwegg-Boussac (Paris-Est Creteil University/IUF)2:30-3:00 p.m. Chris Thornhill (University of Birmingham): The Military in Sociological Constitutionalism3:00-3:15 Discussion3:15-3:45 p.m. Coffee Break3:45-4:15 p.m. Jörn Reinhardt (Fulda University of Applied Sciences): Regression and Progress in Constitutionalism beyond the State4:15-4:45 p.m. Martin Loughlin (LSE): The Concept of Constitution4:45-5:15 Discussion5:15 p.m. Cocktail 

After a presentation of the book, Déborah V. Brosteaux will be interviewed by Thibault De Meyer and Vivien Giet.Free admission. Everyone is welcome.Book presentationFaced with the wars in which European countries are involved, we constantly oscillate between numbness and frenzy. Some war situations give rise to emotional heatedness, a "renewed" psychic and social energy, while others are barely mentioned, relegated to the background. This philosophical investigation delves into the ambivalence of our relationship to war, which is at the heart of the sensitive history of modernity.Inspired by the writings of Walter Benjamin, W. G. Sebald, and Klaus Theweleit, the book explores these warlike emotions throughout the 20th century and questions their legacy: the coldness of distancing, the denial of the ruins after 1945, the desire to intensify the experience of self, which mobilized the imagination in 1914-1918 and was swallowed up in the trenches... even mutating into fascist passions that actively fed on the devastation.Déborah V. Brosteaux takes these desires seriously, including their appeal. And she asks: what emotional transformations can be activated to resist the mobilization of war?  More information about the ARCADIE Center