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Abstract Radiotherapy is a cornerstone of cancer treatment and is currently administered to approximately half of all cancer patients. However, the cytotoxic effects of ionizing radiation on normal tissues represent a major limitation, as they restrict the dose that can be safely delivered to patients and, consequently, reduce the likelihood of effective tumor control. In this context, delivering radiation at ultra-high dose rates (UHDR, > 40 Gy/s) is gaining increasing attention due to its potential to spare healthy tissues surrounding the tumor and to prevent radiation-induced side effects, as compared to conventional dose rates (CONV, on the order of Gy/min).The mechanism underlying this protective effect-termed the FLASH effect-remains elusive, driving intensive research to elucidate the biological processes triggered by this type of irradiation.In vitro models offer a valuable tool to support this research, allowing for the efficient screening of various beam parameters and biological responses in a time- and cost-effective manner. In this study, multicellular tumor spheroids and normal cells were exposed to proton irradiation at UHDR to evaluate its efficacy in controlling tumor growth and its cytotoxic impact on healthy tissues, respectively.We report that UHDR and CONV irradiation induced a comparable growth delay in 3D tumor spheroids, suggesting similar efficacy in tumor control. In normal cells, both dose rates induced similar levels of senescence; however, UHDR irradiation led to lower apoptosis induction at clinically relevant doses and early time points post-irradiation.Taken together, these findings further highlight the potential of UHDR irradiation to modulate the response of normal tissues while maintaining comparable tumor control.JuryProf. Thomas BALLIGAND (UNamur), PresidentProf. Stéphane LUCAS (UNamur), SecretaryProf. Carine MICHIELS (UNamur)Dr Sébastien PENNINCKX (Hôpital Universitaire de Bruxelles)Prof. Cristian FERNANDEZ (University of Bern)Dr Rudi LABARBE (IBA)

The conference is co-organized by the University of Namur, Belgium and Wuhan University of Technology, China and supported by Foshan Xianhu Laboratory and other organisms.More info on the GCMC2025 website...

Welcome to the 1ʳᵉ MG-ERC conference This conference, linked to the research themes of the Chemistry Department, aims to bring together around 100 researchers working in the fields of heteroatom chemistry, coordination chemistry, catalysis, and inorganic chemistry. It represents a real novelty in Belgium in terms of the areas covered, and will enable participants to discover new concepts, ideas and trends in these recent areas of research in chemistry. Here is the list of speakers, who are world experts in their fieldsDr. Daniël Broere (Utrecht University, Netherlands)Prof. Agnieszka Nowak-Król (Universität Würzburg, Germany)Dr. Antoine Simonneau (Université Paul-Sabatier, Toulouse, France)Prof. Dr. Sebastian Riedel (Freie Universität, Berlin, Germany)Dr. Arnaud Voituriez (Université Paris-Saclay, France)Prof. Dr. Alessandro Bismuto (Universität Bonn, Germany)Dr. Christian Hering-Junghans (Leibniz-Institut für Katalyse, Germany)Prof. Connie Lu (Universität Bonn, Germany)Prof. Simon Aldridge (University of Oxford, UK)Dr. Ghenwa Bouhadir (Université Paul-Sabatier, Toulouse, France)Prof. Dr. Viktoria Däschlein (Universität Bonn, Germany)Prof. Viktoria Däschlein-Gessner (Ruhr-University of Bochum, Germany)Dr. Jennifer A. Garden (University of Edinburgh, UK)Prof. Muriel Hissler (Université de Rennes, France)Prof. Jean-François Paquin (Université de Laval, Canada) More information and registration

Program 8:50 | Welcome, registration, and poster setup9:20 | Welcome speechFirst morning session 9:30 | Vladimir N. Uversky - University of South Florida, USA - "Dancing protein clouds: strange biology and chaotic physics of intrinsically disordered proteins" 10:15 | Marie Skepö - Lunds Universitet, Sweden - "Structural and conformation properties of IDPs: computer simulations in combination with experiments" 11:00 | Coffee breakSecond morning session11:30 | Peter Tompa - Vrije Universiteit Brussel, Belgium - "Fuzzy interactions of IDPs driving biomolecular condensation"12:15 | Sonia Longhi - Aix-Marseille Université, France - "Intrinsic disorder, phase transitions, and fibril formation by the Henipavirus V and W proteins"13:00 | Lunch and poster sessionAfternoon session14:30 | Sigrid Milles - Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Germany - "Intrinsically disordered proteins in endocytosis: an NMR and single molecule fluorescence perspective"15:15 | Jean-François Collet - Université Catholique de Louvain, Belgium - "How disorder controls the transport of lipoproteins in the cell envelope of Gram-negative bacteria" 16:00 | Closing speech16:10 | Networking Beer Time at "Le Chapitre"VenueUniversity of Namur, auditorium Pedro Arrupe (PA02), rue de Bruxelles, 65-67 - 5000 Namur (#21 on the campus map) Download the programme (PDF) Download the campus map Registration guidelines Registration feeStudents (PhD students included): 25 €Seniors: 40 €Payment - Bank transferPayable before 6 December on the account:Name: Université de Namur - ASBLIBAN: BE10 2500 0740 2704BIC: GEBABEBBPlease mention your name/CPO4136330 /e-mail in the payment communication. Abstract guidelines Send us your abstract before 6 December by email: pdid.meeting@unamur.beFormat: Word document, maximum 1 page A4, Times New Roman  Registration All deadlines (registration, payment, abstracts) : 6 December 2024

At the end of January 2023, the Metropolitan Museum of Art (New York) returned a real treasure to Belgium: a medieval charter bearing the seal of the Count of Flanders Philippe d'Alsace, formerly kept in the abbey of Messines (West Flanders), which had disappeared at the beginning of the First World War. A look back at the tribulations of this archival document, the restitution of which is the result of a fruitful collaboration between the PraME Centre of UNamur, the General Archives of the Kingdom and the Ministry of Foreign Affairs.

The Department of Art History and Archaeology of UNamur is participating for the first time in an experimental archaeology project, within the framework of a doctoral thesis on the production of glass in the Roman period. Conducted in partnership with Malagne, the Rochefort archaeopark, the Specularia project aims to gain a better understanding of the reality of the gestures and techniques of Gallo-Roman craftsmen and to scientifically validate hypotheses that are still debated today. To carry out this experiment, the Department of Art History and Archaeology is launching its first participatory funding.

This is a first at the UNamur: a team of archaeologists will soon be testing an experimental protocol to reproduce the process of shaping glass in Roman times. Entitled Specularia (Latin for "glass"), this project has the support of several associations and companies, including AGC Glass Europe.

The documentary produced as part of the experimental archaeology research project, "Specularia", wins an award at an American festival, organized by the University of Pittsburgh and the University of South Carolina!

Angélique Aristondo, a C2W post-doctoral fellow at UNamur, has distinguished herself by winning the second 2023 Gender and Health Research Award from the ARES Women and Science Committee. Her research project focuses on violence against women in Senegal.

What exactly did the ancient Egyptians eat? How did they prepare and preserve their food? What was their nutritional value? René Preys, an Egyptologist at UNamur, is currently involved in this astonishing research. This expert is a major figure in Belgian Egyptology. Interview.

Space has become a major economic and strategic issue. As a member of the European UNIVERSEH Alliance, UNamur explores this space theme in its various departments, from physics to geology, via mathematics, computer science or philosophy. Without forgetting to address the general public, who still dream of the stars...

Two researchers from the Institut Patrimoines, Transmissions, Héritages (PaTHs) have just been awarded funding from the F.R.S - FNRS following calls whose results were published in December 2024. The PaTHs institute is a federation of research centers and groups that have sprung up in and around the Faculty of Philosophy and Letters. The institute is distinguished by its emphasis on critical analysis of the "traces" of the past (written, material, monumental, landscape, visual, sound...), to the point of placing the "trace" itself at the heart of scientific questioning.