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The Elongator complex is involved in the addition of 5'-carboxylmethyluridine (cm5U)-derived modifications to transfer RNAs (tRNAs), thereby influencing the translation of certain messenger RNAs (mRNAs) and helping to maintain the integrity of the proteome. This complex is involved in a variety of biological processes, and is of particular importance in oncology. The identification of chemical inhibitors of Elongator is of significant interest in both basic and pharmaceutical research.Through a yeast screen, this work reveals a potential new role for Elongator and identifies a chemical inhibitor of the complex. This compound presents itself as an interesting candidate as a pharmacological inhibitor, opening up new perspectives for the search for anti-cancer therapies.

COVID-19 is an infectious disease caused by SARS-CoV-2. COVID-19 was quickly declared a pandemic by the World Health Organization (WHO) on March 11, 2020.At the start of the pandemic, healthcare professionals were faced with the marketing of numerous kits designed to measure binding antibodies. The role of neutralizing antibodies as the best correlate of protection against SARS-CoV-2 infection was quickly highlighted. A neutralization assay with the use of pseudovirus was therefore developed by our team and compared with several binding assays.There have been considerable efforts to produce and clinically validate new vaccines against COVID-19. The CRO-VAX HCP study was designed to assess the humoral response in a population of healthcare professionals who had received two doses of COVID-19 BNT162b2 vaccine.Given the decline in vaccine efficacy over time and the emergence of variants likely to evade immunity, a third dose was quickly recommended by the authorities to boost immunity. This was administered to 155 volunteers in the CRO-VAX HCP study.Still facing a decline in vaccine efficacy over time and the emergence of new variants, a second adapted booster was proposed. In September 2022, 54 participants in the CRO-VAX HCP study received this second booster. The humoral response was assessed and neutralizing antibodies against several variants were measured. In addition, we also measured the cellular response using an interferon-gamma release assay. Compared with the humoral response, which declines considerably over time, the cellular response remained fairly stable. This could therefore explain why individuals with low antibody titers can still be protected against a severe form of the disease .

Three themes will be addressed by various experts:The objectification of rurality and shortagewith the participation of AVIQ and IWEPSLevers for changewith examples from doctors in the field, the participation of Communes and the SSMGMedical on-call care in rural areasthe example of Luxembourg, Sivry-Rance and Namur

Doctors will be able to track their participation in continuing education via their INAMI number. More info and registration Members and students of the University of Namur are invited to register for the conference on 31/01/2025 here...

Why "One Health"? Human, animal and environmental health are closely interrelated. The aim of this new teaching unit is to train future healthcare professionals in a global and interdisciplinary approach to health, taking these complex interactions into account. The program Speeches by Ms Annick Castiaux, Rector of UNamur and Mr Grégoire Wiëers, Director of the Department of MedicineOpening speech by Mr Yves Coppieters, Minister of HealthPresentation of the teaching unit and its objectivesExchange with future students and healthcare professionalsCocktailRegistration free but compulsory. I want to register

The profound transformation of the healthcare context that we have been witnessing for many years requires the training of healthcare professionals to be adapted. Since September 2021, Hénallux has been offering a Master's degree in Nursing, in codiplomation with HEPN, HELHA, UCLouvain and UNamur. This is a joint Hautes Écoles-Universities Master's degree of 120 credits, programmed to combine study and work.Accreditation in ethics and economics required.Participation: 85 eurosPreferential rate for students from a consortium (including UNamur): 25 eurosMore info and registration: https://www.henallux.be/journee-scientifique-du-master-en-sciences-infirmieres

Target audienceGeneral practitioners (in practice or in training)PharmacistsMedical and pharmacy studentsObjectivesShare and discuss scientific articles relevant to frontline practice in a friendly and caring atmosphereStrengthen skills in critical reading and evidence-based medicineCreate a lasting link between the field and the academic worldFederate an active and committed medico-pharmaceutical community.pharmaceutical communityWhy participate?Because science moves fast, and we all benefit from taking the time to read, understand, and question the literature together. Because quality care starts with shared reflection. And because it's the ideal opportunity to strengthen bridges between disciplines.Location and frequency of meetingsUNamur - Quai22 - 2 times a yearFirst meeting: 5/06/2025 (free with registration)INAMI accreditation required. I want to register

Take part in our open morning Given the works in the rue de Bruxelles and the renovation of part of the University parking lots, we invite you to use public transport whenever possible (train or bus) to reach Namur. UNamur boasts an ideal location, in the heart of the city just a five-minute walk from the TEC and SNCB train stations.If you're coming by car, take a look at the parking map provided. Look forward to seeing you on Saturday, June 29!

Save the date! On Saturday June 28, 2025, from 1pm to 5pm, UNamur once again opens its doors to you before the summer vacations.At the programProfessors, assistants, students and staff members look forward to welcoming you to answer all your questions about your future studies;share with you their experience of university life and its many opportunities for fulfillment;guide you through your final practical steps: registration, preparatory courses, finding accommodation, financial aid and more.Forthcoming informationThe afternoon's detailed program will be available some ten days before the event. Find out more about the open house

A program for every discipline During late August and early September, UNamur offers rheto students preparatory courses tailored to their future training.These revision sessions are specially designed to support students in their transition to university. By reinforcing their foundations in the key subjects of their future discipline, they enable them to approach their first year with confidence. These preparatory courses are also an excellent opportunity to discover the campus, meet future classmates and familiarize themselves with the learning methods specific to higher education. Discover the preparatory courses Preparation for the medical entrance exam For students wishing to begin studying medicine, two sessions are also organized according to a specific timetable to prepare for the entrance exam. Discover the preparatory courses for the entrance exam to medicine

In practice Who are open courses for?Open courses are open to all, although they are primarily aimed at secondary school students to help them take that first step in exploring higher education.What is the schedule for open courses?Courses are open from February 27 to Wednesday, March 5, 2025, from 08:30 to 16:30.To find out the precise timetable and location of each course, please visit the Info études service (Rue de Bruxelles, 85 5000 Namur), 15 minutes before the start of the course.The provisional program is available 15 days before the start of open courses.How to meet a guidance counselorYou have the opportunity to meet a guidance counselor at the guidance workshop scheduled for Tuesday, March 4, 2025, from 1:30 to 4:00 pm.The aim of this workshop is to help you think about the guidance process, gain a better understanding of the higher education landscape and define the main markers in the process of clarifying your project (educational and professional).Our advisor is also available by appointment for a one-to-one meeting throughout the week of open courses and outside of it.Do you have to register to take part?Access to open courses is without prior registration.To participate in the orientation workshop, however, online registration is mandatory and will be available some ten days before the start of the open courses.Who organizes the open courses?Open courses are organized by Info études, the service that provides information on all matters relating to choice of studies, prerequisites, reorientation, gateways, course curricula, job opportunities, additional training, recognition of prior learning... or any general questions about university life in Namur. Find out more about open courses

Save the date! The next UNamur Open House will take place on Saturday, March 29, 2025, from 1pm to 5pm.Save this date in your diary already!!On the programInspiring encounters: chat with our professors, assistants and students.Immersive tours: explore our auditoriums, classrooms and laboratories.Valuable information: get answers to all your questions about our programs and the specifics of studying in Namur.Practical resources: discover all the services available to support you before, during and after your studies.Stay tuned!The detailed afternoon program will be available some ten days before the event.Can't join us? No worries! A second open house is scheduled for Saturday, June 28, 2025, from 1pm to 5pm. Find out more about the open house