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Abstract Estrogens originating from human and animal excretion, as well as from anthropogenic sources such as cosmetics, plastics, pesticides, detergents, and pharmaceuticals, are among the most concerning endocrine-disrupting compounds in aquatic environments due to their potent estrogenic activity. While their effects on fish reproduction are well documented, their impact on development, particularly metamorphosis, remains poorly studied. This hormonal transition, mainly controlled by the thyroid axis, is essential for the shift from the larval to the juvenile stage in teleosts.The effects of two contraceptive estrogens on zebrafish (Danio rerio) metamorphosis were evaluated: 17α-ethinylestradiol (EE2), a synthetic reference estrogen, and estetrol (E4), a natural estrogen recently introduced in a new combined oral contraceptive formulation. Continuous exposure from fertilization to the end of metamorphosis allowed the assessment of morphological changes, disruptions of the thyroid axis, and modifications of additional molecular pathways potentially involved in metamorphic regulation.EE2 induced significant delays and disturbances in metamorphosis, affecting both internal and external morphological traits, confirming its role as an endocrine disruptor of concern. In contrast, E4 did not cause any detectable morphological alterations even at concentrations far exceeding those expected in the environment, indicating a limited ecotoxicological risk. Molecular analyses showed that EE2 strongly affected thyroid signaling and energy metabolism during metamorphosis, whereas E4 induced only minor transcriptional and proteomic changes.This study provides the first evidence that EE2 can disrupt zebrafish metamorphosis and highlights the importance of including this developmental stage in ecotoxicological assessments. The results also suggest a larger environmental safety margin for E4, although further research is needed to clarify the mechanisms linking estrogen exposure to metamorphic regulation.JuryProf. Frederik DE LAENDER (UNamur), PresidentProf. Patrick KESTEMONT (UNamur), SecretaryDr. Sébastien BAEKELANDT (UNamur)Dr. Valérie CORNET (UNamur)Prof. Jean-Baptiste FINI (Muséum National d'Histoire Naturelle, Paris)Dr. Marc MULLER (ULiège)Prof. Veerle DARRAS (KULeuven)

On the occasion of the International Day of Women and Girls in Science proclaimed on February 11 by the United Nations General Assembly, and as part of the European alliance European Space University for Earth and Humanity (UNIVERSEH) focusing on the theme of space, discover the testimonies of four women scientists from UNamur working on astronomical themes.

In an ever-changing world, where health, environmental and societal crises are intertwined, it is becoming imperative to rethink health in a global and interconnected approach. It was against this backdrop that the Faculty of Medicine at the University of Namur inaugurated its new "One Health" teaching unit (UE) on Thursday February 06, 2025, in the presence of Minister Yves Coppieters. This initiative, offered to all UNamur undergraduates, aims to train tomorrow's healthcare professionals in a systemic vision, where human, animal and environmental health are considered as one and the same reality.

Helping us to age independently and in good health. This is the aim of Charlotte Beaudart's research into sarcopenia, an age-related disease that can occur as early as the age of 50. The work of the UNamur researcher and member of the Narilis Institute has been rewarded once again, as she has just been awarded the title of "Namuroise of the Year", for the Sciences category!

Founded some 50 years ago, the Laboratoire d'Analyse par Réactions Nucléaires (LARN) in the Department of Physics at the University of Namur is home to a 2MV tandem particle gas pedal named ALTAÏS (Accélérateur Linéaire Tandetron pour l'Analyse et l'Implantation des Solides), in operation since 1999.

Thomas Balligand, now a lecturer at UNamur, combines his passion for basic research with teaching in histology and cytology. After a diverse background in internal medicine and research, notably at Harvard, he is dedicated to training the next generation of scientists while pursuing his work on nanobodies and their potential in immunotherapy. His desire to awaken scientific curiosity in his students illuminates his new role at the university..

A major breakthrough for the health of women on oral contraceptives has been achieved by researchers in Namur. Every year in Europe, more than 22,000 cases of venous thrombosis or embolism occur among contraceptive pill users. A team of researchers from the University of Namur, in collaboration with QUALIblood (spin-off), has conducted an important study, the results of which could transform prescribing recommendations..

Bringing a new drug to market, particularly when it is intended to treat a pediatric or orphan disease, is a journey fraught with pitfalls. The ERAMET project, coordinated by Professor Flora Musuamba Tshinanu, aims to overhaul the assessment procedures, so that regulatory agencies can take innovative technologies into account and thus make more informed choices.

For about a decade, a disease has been attracting the attention of the medical community. Its name: sarcopenia. This condition affects more than 10% of people over the age of 65 and is characterized by a significant loss of muscle mass and strength. Charlotte Beaudart, a member of the Department of Biomedical Sciences and the NARILIS Research Institute, has made a name for herself on the international stage in recent years by contributing to a better understanding of this disease and raising awareness about it.

In the coming months, the University of Namur will participate in an exceptional space mission aboard the International Space Station (ISS), alongside Belgian astronaut Raphaël Liégeois. The BeBlob project, led by researchers Boris Hespeels (ILEE Institute) and Anne-Catherine Heuskin (NARILIS Institute), aims to study the DNA repair capabilities of a fascinating organism: the blob (Physarum polycephalum).

At UNamur, parchments are much more than objects of curiosity: they are at the heart of an interdisciplinary scientific adventure. Starting with historical sciences and conservation, the research has gradually incorporated the disciplines of physics, biology, chemistry, and archaeology.  This convergence has given rise to research in heritage sciences, driving innovative projects such as Marine Appart's doctoral work, supervised by Professor Olivier Deparis. This research has now been recognized with a publication in the prestigious journal Heritage Science (Nature Publishing Group).

The IBAF Meetings have been organized since 2003, every two years since 2008, by the Ion Beams Division of the French Vacuum Society (SFV), the oldest national vacuum society in the world, which celebrated its 80th anniversary in 2025.As in previous editions, IBAF 2026 will offer a rich and varied program with guest lectures, oral and poster presentations, and technical sessions. All this will be complemented by an industrial presence to promote exchanges between research and innovation. The conference will cover a wide range of topics, from ion beam instruments and techniques to the physics of ion-matter interactions, including the analysis and modification of materials, applications in the life sciences, earth and environmental sciences, and heritage sciences. More information on the IBAF2026 website