The first two modules are organized as lectures (2 X 2h). Each course is taught by a first-year bachelor's professor.
Essential structures and functions of eukaryotic cells; introduction to cell division
The course provides an overview of the different cellular compartments in an animal and plant cell. The different organelles of the cell are then described from a structural point of view and from the point of view of their main function in the cell. The cell cycle and the process of cell division are recapped.
Macromolecules of life; the genetic code and its translation into proteins
The course reviews different macromolecules of living things: lipids (energy source, phospholipids and sterols), proteins (4 levels of organization, structure-function-activity relationship) and nucleic acids (nucleotides, RNA, DNA, double helix, hereditary material).
The following modules (3 X 2h) are organized in groups of more or less 25 students. They are taught by assistants from the Biology department.
Metabolism I: notions of enzymes, energy and ATP, catabolism and anabolism
The points covered are:
- Some thermodynamic aspects
- Free energy, endergonic and exergonic reactions, balanced reactions, energy coupling, catabolism-anabolism link
- Carbohydrates, storage and reserve polysaccharides
- ATP, energy currency of the cell, examples of production
- Enzymes, activation energy, active site, allosteric regulation, inhibitors, denaturation
Metabolism II: Energy flow in the cell (respiration and photosynthesis)
Points covered are:
- Autotrophs, heterotrophs
- Fundamental role of ATP
- Energy-producing metabolisms
- Aerobic cellular respiration
- Fermentation
- Photosynthesis
Mendelian genetics, meiosis, crossover and related genes
The points covered are:
- Historical background to the birth of genetics
- Recall of meiosis and comparison with mitosis
- Mendel's laws
- Phenotype and genotype
- Test-cross
- Codominance, partial dominance, polyallelic and polygenic heredity, pleiotropy, epistasis
- Sex chromosome-related heredity
- Gene linkage, spanning, genetic map.