Learning outcomes

Understanding and knowledge of major asymmetric synthesis methods

Understanding and knowledge of major asymmetric catalysis methods

Understanding of the interest of sigmatropic and dyotropic reactions

Understanding of non-linear effects, chiral amplification and autocatalysis, their mechanistic implications and their importance in the contect of homochirality

 

Goals

The aim of the course  is to give advanced knowledge of asymmetric catalysis and synthesis.

 

Content

The main families of stereoselective and enantioselective reactions are reviewed.

 

Table of contents

I. Asymmetric Synthesis
II. Asymmetric Catalysis
III. Non-linear Effects and Chiral Amplification
IV. Chiral Organometallics and Organometallic Catalysis
V. Dyotropic Reactions in Synthesis

Exercices

n/a

Assessment method

The course is evaluated by a personal report and presentation on a timely topic in asymmetric synthesis or catalysis.

Sources, references and any support material

Lecture slides are available in PDF format.

Additional reading:
L. Kvaerno, E.M. Carreira : Classics in Stereoselectuve Synthesis

 

Language of instruction

Français