To understand how an animal (mainly human) eukaryotic cell responds to stimuli from its environment, in terms of proliferation and growth, differentiation and programmed cell death. To understand the intervention of the deregulation of these mechanisms during the development of cancer cells.
To achieve competence in understanding the mechanisms involved in initiating cell growth, differentiation and death; to know the main regulators involved in controlling these phenomena; to understand the regulatory mechanisms and their deregulation in pathological situations, particularly cancer.
Cell growth and differentiation and their normal and pathological control. Signal transduction pathways from stimulus perception (receptor) to regulation of gene expression that are responsible for the adapted cellular response. Apoptosis and autophagy: mechanisms and regulations.
Written exam: duration 2h30. This examination generally consists of open questions and MCQ questions relating to the parts taught by each teacher. A result of less than 7/20 in either part of the examination will cap the total result at 9/20. The exact modalities of the evaluation are subject to change when the examination timetable is drawn up, depending on the practical constraints that the faculty administration may face, or in the event of illness/force majeure/emergency with a placement, preventing the student from taking the examination on the date initially scheduled.
For the part taught by Professor Poumay, the books "Molecular Biology of the Cell" (Alberts et al.) and "The Biology of Cancer" (Weinberg) are useful basic references (available at the BUMP). For the part taught by Professor Arnoud, the course materials and journal or research articles are references to be read.
| Training | Study programme | Block | Credits | Mandatory |
|---|---|---|---|---|
| Bachelier en sciences biomédicales | Standard | 0 | 3 | |
| Bachelier en sciences biomédicales | Standard | 3 | 3 |