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The lysosome, a small intracellular organelle, is often represented as the stomach of the cell due to its acidity and the presence of numerous digestive enzymes within it. Its role? The degradation of numerous molecules and their recycling to build new molecules and fuel energy production in the cells. Since 2003, Marielle Boonen has been particularly interested in the lysosome. Together with researchers from UNamur, she has highlighted the role of a lysosomal enzyme called HYAL1 in the bone remodelling process.

To restore an old book correctly, it is essential to know the secrets of its manufacture and the reasons for its deterioration. Thanks to the King Baudouin Foundation's Jean-Jacques Comhaire Fund, the restoration workshop of the Moretus Plantin University Library has launched a new research project on parchment bindings in the Southern Netherlands in the 16th and 17th centuries. The aim is to gain a better understanding in order to improve conservation.

In 1996, the European Union created the Marie Skłodowska-Curie Actions (MSCA), a set of prestigious and competitive grants designed to fund research. Thanks to her, the PROSTAMET project got underway on January 1, an ambitious program focused on training PhD students and discovering new therapeutic avenues against prostate cancer, in which UNamur is participating.

The absorption of light by molecules has applications in microscopy, medicine and data storage. With this research, the researcher from the UNamur NISM institute fills an experimental gap, which will enable molecular engineers to develop new and more efficient compounds in their various fields of application.

Yves Caudano, F.R.S.-FNRS qualified researcher, member of the NaXys and NISM Institutes and the UR-LLS (Lasers and Spectroscopies Laboratory) research unit, is taking part in a major European research project. The aim? To find new quantum light sources with unprecedented versatility, flexibility and performance.

On 13 December 2023, Charlotte Beaudart, a new academic at the University of Namur Faculty of Medicine, will be awarded a prize at the annual ceremony for Belgian scientific research in support of her innovative research on the subject of ageing.

Dr. Sébastien Mouchet, a researcher at UNamur and member of the NISM and ILEE Institutes, has just published the results of research focusing on the effects of pollution on coral reef fish in MDPI-Optics. The findings of the international, multidisciplinary team lead to crucial conclusions with implications for the health of marine ecosystems.

The Elongator complex is involved in the addition of 5'-carboxylmethyluridine (cm5U)-derived modifications to transfer RNAs (tRNAs), thereby influencing the translation of certain messenger RNAs (mRNAs) and helping to maintain the integrity of the proteome. This complex is involved in a variety of biological processes, and is of particular importance in oncology. The identification of chemical inhibitors of Elongator is of significant interest in both basic and pharmaceutical research.Through a yeast screen, this work reveals a potential new role for Elongator and identifies a chemical inhibitor of the complex. This compound presents itself as an interesting candidate as a pharmacological inhibitor, opening up new perspectives for the search for anti-cancer therapies.

More info coming soon! More info on the NARILIS website

The NISM Institute's Multi-scale Modeling through High-Performance Computing (HPC-MM) cluster aims to share techniques, skills and computational tools to develop new materials and predict their final properties. It also aims to improve modeling techniques and computer codes to take into account most of the chemistry and physics of structured matter.

Research at NISM is identified by four poles, which highlight the main scientific activities carried out within the institute. Each pole has a well-defined structure with members, and is managed by the pole representative. The structuring does not prevent ongoing cooperation between them. Indeed, there is well-established interaction between the various clusters, through joint projects, conferences, seminars, co-supervision of master's and doctoral theses, among others..

The Nonlinear Optics and Photonics cluster (NOP) develops experimental, theoretical and numerical research in various fields of optics, mainly in nonlinear optics and photonics, including plasmonics and quantum optics.