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The Elongator complex is involved in the addition of 5'-carboxylmethyluridine (cm5U)-derived modifications to transfer RNAs (tRNAs), thereby influencing the translation of certain messenger RNAs (mRNAs) and helping to maintain the integrity of the proteome. This complex is involved in a variety of biological processes, and is of particular importance in oncology. The identification of chemical inhibitors of Elongator is of significant interest in both basic and pharmaceutical research.Through a yeast screen, this work reveals a potential new role for Elongator and identifies a chemical inhibitor of the complex. This compound presents itself as an interesting candidate as a pharmacological inhibitor, opening up new perspectives for the search for anti-cancer therapies.

More info coming soon! More info on the NARILIS website

will take place from September 2 to 6, 2024 at the Gîte du domaine d'Haugimont (owned by the University of Namur) and will deal with medieval manuscripts in their material and historical aspects (parchment and ink manufacture). The event is aimed at historians, archaeologists and researchers in the physical and chemical sciences. Participation is free for doctoral students attached to FNRS doctoral schools in the disciplines concerned. At the crossroads of archaeology, history and the exact sciences, this colloquium-workshop will give the floor to three speakers (a physicist, a chemist and a historian) who will present the interdisciplinary research they are conducting together in this field. Workshops on parchment reproduction, inks and writing materials will be held each day.More information on the event .

The wolf, long banished from our lands, has made a remarkable comeback in Wallonia since 2016. This mysterious being, now protected, arouses as much fascination as fear. Through an exhibition, held as part of the Cultural Project course, third-year history bachelor students have traced the history of the wolf. From April 11 to 27, 2024, the exhibition entitled "Même pas peur! Une évolution de l'image du loup à travers les siècles" invited audiences to plunge into the heart of a historical exploration.

In an ever-changing world, where health, environmental and societal crises are intertwined, it is becoming imperative to rethink health in a global and interconnected approach. It was against this backdrop that the Faculty of Medicine at the University of Namur inaugurated its new "One Health" teaching unit (UE) on Thursday February 06, 2025, in the presence of Minister Yves Coppieters. This initiative, offered to all UNamur undergraduates, aims to train tomorrow's healthcare professionals in a systemic vision, where human, animal and environmental health are considered as one and the same reality.

Helping us to age independently and in good health. This is the aim of Charlotte Beaudart's research into sarcopenia, an age-related disease that can occur as early as the age of 50. The work of the UNamur researcher and member of the Narilis Institute has been rewarded once again, as she has just been awarded the title of "Namuroise of the Year", for the Sciences category!

The TineaDiag project is a research project run by UNamur and ULiège with funding from the SPW Research Win²WAL program. It tackles dermatophytoses, skin infections responsible for ringworm, which can affect both humans and animals. The aim? To identify, in dermatophytes, precise cellular markers in order to detect them with sensitivity and certainty, and thus identify infections caused by antifungal-resistant strains.

Research centers AcanthuM (Monumental, archaeological and artistic heritage) See content ARaiRe (Recherches namuroises en histoire Rurale, 1500-1850) See content Fontes Antiquitatis center See content HiSI research center (History, sounds and images) See content Pratiques médiévales de l'écrit (PraME) research center See content

Contacts Fulgence DELLEAUX +32 (0)81 72 41 93 fulgence.delleaux@unamur.be Jean-François NIEUS +32 (0)81 72 41 94 jean-francois.nieus@unamur.be

David Bardey (PraME)Disappearance of jewels and letters at the abbey. Enquête sur les héritages de Guillaume de Vienne, seigneur de Saint-Georges (Cîteaux, 1344)Alexis Fontbonne (PraME)La notion de champ ecclésial

Chantal Senséby (Université d'Orléans), Adjustments textuels, ajustements sociaux et politique seigneuriale. Acts of entry into servitude (Western France, 10th-early 11th century)

If interdisciplinarity is a buzzword within the academic bureaucracy, it's hard to conclude that it exists in practice. Embracing a slogan does not an epistemology make, and claiming progress is no guarantee of it. To prevent the interdisciplinary approach from being reduced to avant-gardism, it is necessary to define the practical conditions for bringing together the different social sciences, going beyond the encounter between academic disciplines or the eclectic taste for the exotic. The eight sessions of the course presented below will seek to provide both a method for the construction of analytical notions by young researchers in history and sociology, and a set of tools favoring the objectification of scientific work in the social sciences.Session 2 - The construction of notions: analytical operators, comparatism and singular conceptsAs the division of labor between sociology as a producer of notions and history as a source of examples constitutes one of the main epistemological obstacles to a consistent practice of historical sociology, it is necessary to define a method for the elaboration of notions that can serve as analytical operators. In this context, the question of comparatism, a term covering diverse and sometimes contrary practices, appears central.Possibility of following the seminar online via Teams