Article

Former UNamur doctoral student featured in The Economist

The research of Dr. Nitin Bharti, a former PhD student in the Economics Department of the EMCP Faculty at the University of Namur, is covered in "The Economist", the prestigious international business magazine. The article deals with one of his favorite research themes: understanding the development of education systems and their link with economic growth and long-term inequality.
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Event

Public defense of doctoral thesis in Physical Sciences - Andrea Scarmelotto

Abstract Radiotherapy is a cornerstone of cancer treatment and is currently administered to approximately half of all cancer patients. However, the cytotoxic effects of ionizing radiation on normal tissues represent a major limitation, as they restrict the dose that can be safely delivered to patients and, consequently, reduce the likelihood of effective tumor control. In this context, delivering radiation at ultra-high dose rates (UHDR, > 40 Gy/s) is gaining increasing attention due to its potential to spare healthy tissues surrounding the tumor and to prevent radiation-induced side effects, as compared to conventional dose rates (CONV, on the order of Gy/min).The mechanism underlying this protective effect-termed the FLASH effect-remains elusive, driving intensive research to elucidate the biological processes triggered by this type of irradiation.In vitro models offer a valuable tool to support this research, allowing for the efficient screening of various beam parameters and biological responses in a time- and cost-effective manner. In this study, multicellular tumor spheroids and normal cells were exposed to proton irradiation at UHDR to evaluate its efficacy in controlling tumor growth and its cytotoxic impact on healthy tissues, respectively.We report that UHDR and CONV irradiation induced a comparable growth delay in 3D tumor spheroids, suggesting similar efficacy in tumor control. In normal cells, both dose rates induced similar levels of senescence; however, UHDR irradiation led to lower apoptosis induction at clinically relevant doses and early time points post-irradiation.Taken together, these findings further highlight the potential of UHDR irradiation to modulate the response of normal tissues while maintaining comparable tumor control.JuryProf. Thomas BALLIGAND (UNamur), PresidentProf. Stéphane LUCAS (UNamur), SecretaryProf. Carine MICHIELS (UNamur)Dr Sébastien PENNINCKX (Hôpital Universitaire de Bruxelles)Prof. Cristian FERNANDEZ (University of Bern)Dr Rudi LABARBE (IBA)
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Research institut

Development Finance & Public Policies

DeFiPP consolidates the research work carried out in three pre-existing centers, CRED, CEREFIM and CERPE, each of which represents one of the three main areas of research: development economics, public policy and regional economics and finance, and monetary economics. DeFiPP's main objective is to promote excellent research in economics and finance, with a high international profile, using economic methodology, both in theory and empirical research, which is the common link between the clusters. Cross-fertilization will take place through the joint sharing of new methods or approaches.

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Research institut

Namur Research Institute for Life Sciences

NARILIS seeks to stimulate two-way interactions between basic researchers and physicians, and to build bridges between the laboratory and the patient's bedside. NARILIS therefore aims to facilitate the translation of basic research findings into clinical applications. Its mission is to promote multidisciplinary research in order to improve human and animal health and quality of life.

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