Learning outcomes

By the end of this course, students will have
- have developed their knowledge and understanding of the functioning of the animal organism at the biochemical level
 

Goals

The student will be able to:
- use biochemical vocabulary
- identify, draw and describe the main structural and functional characteristics of living molecules (in particular: lipids, amino acids, peptides, proteins)
- understand the conformation-function relationship of proteins (based on selected examples)
- understand the concepts underlying enzyme catalysis (enzyme classification, kinetics, enzyme inhibition, catalytic mechanisms, etc.)
- identify and explain the principle of some basic techniques used in biochemistry and cell biology
- identify the role and correct positioning of key players in selected intracellular processes
- identify and explain the molecular basis of selected examples of human diseases (amino acid transport diseases, diseases associated with peptic or protein destructuring)
- read and interpret scientific data presented in graphical form
- solve biochemical exercises related to the subject taught

Content

- descriptive biochemistry: lipids, amino acids and proteins
- amino acid transport diseases: some molecular and cellular concepts
- primary, secondary, tertiary and quaternary protein structures
- protein folding and maturation
- neurodegenerative diseases associated with peptide or protein destructuring: some basic concepts
- proteins: structure/function relationships (myoglobin and hemoglobin)
- Enzymology: kinetics (Michaelis-Menten equation), enzyme catalysis, enzyme inhibitors (general concepts and examples of clinical importance)

Assessment method

Written exam including MCQs and/or open-ended questions.
 

Sources, references and any support material

- specific materials posted on webcampus
 
- reference books (not essential):
   Lehninger, Principles of Biochemistry (Nelson, Cox): Freeman
   Harper Biochemistry (Murray, Bender, Botham, Kennelly, Rodwell, Weil): de boeck
 

Language of instruction

Français
Training Study programme Block Credits Mandatory
Bachelier en médecine vétérinaire Standard 0 3
Bachelier en médecine vétérinaire Standard 2 3