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Let's go and discover the qualified researchers of UNamur, winners of the funding granted by the FNRS in 2022. Today, we meet Michaël Lobet, currently a lecturer at UNamur, who will begin his new mandate as a qualified FNRS researcher at the NISM Institute next fall. The subject of his research: twisted optics for the manipulation of slow photons or how to create light traps. Explanations.

An international team of physicists led by Dr Michaël Lobet, lecturer at UNamur, re-examines the foundations of quantum physics from the point of view of momentum in the prestigious journal Nature Light Science & Applications. The researchers investigated what happens when this momentum is reduced to zero. Some interesting things happen! Explanations.

Prof. Olivier Deparis and Dr Sébastien Mouchet (University of Namur, NISM Institute, Department of Physics) have published a book on the theme of physical optics and environmental biology. On the path of Jean-Pol Vigneron’s research, this “avant-garde” book according to Artech House, opens the door to bioinspired applications in the fields of optics, energy and the environment. Explanation.

What is a perfect fluid? It is a theoretical model of a fluid that allows us to assume that the fluid is not viscous, that it does not conduct heat, that it is incompressible and does not create vortices. It is therefore an approximation of reality that simplifies theoretical predictions of fluid flows. For the first time, an international team has experimentally demonstrated this same behaviour for light immersed in a medium of low refractive index.

On 9 June 2023, the NISM and naXys Institutes, the Physics and Chemistry Departments and the Namur Research College were delighted to welcome Prof. Jean-Luc Brédas from the University of Arizona. A prestigious speaker of international renown, Prof. Brédas completed his doctoral thesis with Prof. Jean-Marie André at the University of Namur.

In January 2023, an international symposium on organic chemistry was held at UNamur in honour of the 80th birthday of Professor Emeritus Alain Krief. A scientific day with six renowned speakers, including Professor Jean-Marie Lehn, 1987 Nobel Prize in Chemistry. Interview.

This is a technical and scientific feat that has just been patented at the UNamur. Researchers from the Laboratory of Analysis by Nuclear Reactions (LARN), the Department of Physics of UNamur (NISM Institute) and the spin-off Innovative Coating Solutions (ICS) have succeeded in developing a carbon-based coating with innovative properties that can be used in a wide range of fields, including fuel cells, decoration, and mechanical parts for automobiles.

Lately, and thanks to LUMI, one of Europe's largest supercomputers, the limits of our knowledge of cell lipid membranes have been pushed back. A team of Namur researchers, including Professor Benoît Champagne and Drs. Pierre Beaujean and Charlotte Bouquiaux, has just published in the Journal of Chemical Information and Modeling. The results of this study pave the way for new approaches in the field of membrane lipid therapy.

One year after receiving funding from the European Research Council (ERC) for his B-Yond project, Prof Guillaume Berionni has just been named a Fellow of the prestigious European chemistry society Chemistry Europe. This distinction makes him the new representative for Belgium for a period of 2 years.

On 21 and 22 September 2023, for the 4th year running, Belgian researchers came together for the bePOM conference. The format was original, with a virtual day and a hybrid day combining virtual and face-to-face sessions. A great success, and a Belgian network that is growing from strength to strength.

An international group of researchers, including Professor Yoann Olivier from the NISM Institute at UNamur, has just published in the prestigious journal Nature. The subject: understanding the microscopic mechanisms that lead to the initialisation, reading and erasing of molecular qubits, a new theme in the study of materials, at the frontier between physics and chemistry.

Characterization of trehalase from Acyrthosiphon pisum for the design of new insecticides SummaryAphids are major pests in agriculture, causing direct damage to plants and acting as vectors for phytopathogenic viruses. Conventional insecticides are widely used to control them, but their toxicity and efficacy pose problems in terms of the environment, human health and the emergence of resistance to these compounds. New alternatives are therefore needed, such as biological control using predators or parasitoids. However, these methods are not always economically viable on a large scale. As part of this thesis, another approach is being explored which involves developing new insecticides targeting the biochemical functions of aphids.The project aims to discover new inhibitors of trehalase, an enzyme essential for insect energy metabolism. Inhibition of this enzyme could disrupt vital insect functions without affecting mammals. This research involved several stages: the purification and complete characterization of trehalase from Acyrthosiphon pisum (the model for this study), the in vivo, in vitro and in silico analysis of commercial inhibitors on this enzyme, before moving on to the search for new inhibitors. Two points of integrated insect management were explored, biological and chemical control.The biological side saw the study of a strain of Streptomyces naturally producing trehalase-inhibiting metabolites, notably validamycin A, a molecule recognized in the literature as one of the best inhibitors, but not applicable as an insecticide. Other molecules appear to have interesting features, but we have not been able to isolate and characterize them.The chemical side has enabled us to create a pharmacophore hypothesis based on experimental results on molecules obtained by virtual screening. Although these molecules are not usable as insecticides as they stand, this hypothesis provides a better understanding of trehalase inhibitors in general and can be used to refine future analyses. JuryProf. Jean-Yves MATROULE (UNamur), presidentDr Catherine MICHAUX (UNamur), promoter and secretaryProf. Frédéric FRANCIS (ULiège), co-promoterProf. André MATAGNE (ULiège)Dr Rudy CAPARROS (ULiège)Dr Morgan HANS (Biocidal)