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The Elongator complex is involved in the addition of 5'-carboxylmethyluridine (cm5U)-derived modifications to transfer RNAs (tRNAs), thereby influencing the translation of certain messenger RNAs (mRNAs) and helping to maintain the integrity of the proteome. This complex is involved in a variety of biological processes, and is of particular importance in oncology. The identification of chemical inhibitors of Elongator is of significant interest in both basic and pharmaceutical research.Through a yeast screen, this work reveals a potential new role for Elongator and identifies a chemical inhibitor of the complex. This compound presents itself as an interesting candidate as a pharmacological inhibitor, opening up new perspectives for the search for anti-cancer therapies.

A bilingual French-sign language dictionary (LSFB), which can be queried in both languages, thanks to cutting-edge technology (facial recognition) and access to a vast database compiling more than 4,500 signs, words and expressions.

Thematic sessionsThe day will be organized in two thematic sessions:Cancer metabolismNew advances in cancer therapyInvited speakersProf. Rebecca FITZGERALD, Early Cancer Institute, University of Cambridge, UKDr. Sébastien DUTERTRE, IBMM, University of Montpellier, FranceProf. Sarah-Maria FENDT, Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven, BelgiumDr. Arnaud BLOMME, Laboratory of Metabolic Regulation, GIGA Institute, University of Liège, Belgium Call for communicationsYoung researchers are invited to submit abstracts for oral communications and posters. All topics related to the field of cancer research are welcome. The deadline for abstract submission is April 1, 2025. Organizing committeeProf. Jean-Pierre Gillet - UNamur, NARILIS, Laboratory of Molecular Cancer BiologyProf. Marc Hennequart - UNamur, NARILIS, Laboratory of Cancer metabolismProf. Marielle Boonen - UNamur, NARILIS, Laboratory of Intracellular Trafficking BiologyProf. Benjamin Beck - ULB, IRIBHMProf. Lionel D'Hondt - CHU UCL Namur, Department of Oncology More info

When a tumour develops in an organism, it is very common for the cancer cells to leave the tumour and move to another organ where they proliferate, creating what are known as metastases. This process is an important factor in mortality, as it means that the disease worsens. Hence the interest in better understanding what happens during this phenomenon. This is what the multidisciplinary team of Carine Michiels, researcher at the NARILIS Institute of UNamur, and Davide Bonifazi, researcher at the University of Vienna, did in the framework of the PACMAN research project financed by the FNRS. The results of this study are published in the journal Neoplasia.

In late November, the Mont-Saint-Guibert-based company Cellistic® donated equipment it no longer used to UNamur. By enabling the university to give this equipment a second life, Cellistic is making an important gesture in support of the development of university research.

EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender). Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.Upon registration - More info and registration on the EMBO website.

Since September 2023, Marc Hennequart, Professor of Biochemistry and Cell Biology at UNamur, has been conducting groundbreaking research into pancreatic cancer. His team, based at the Faculty of Medicine and the Institut Narilis, studies the early stages of oncogenesis (the process of transforming a normal cell into a cancerous one) to better understand the metabolic changes behind this particularly aggressive cancer.

In the course of 2021, 42% of Belgian companies suffered a cyber attack. Those targeting citizens are no less numerous: more than 4.5 million suspicious messages have been sent to Safeonweb, the government body responsible for informing Belgian citizens about computer security. More than ever, at a time when the geopolitical context reinforces the threat of a cyberwar, how can we cope? Jean-Noël Colin, cybersecurity expert, professor at the Faculty of Computer Science of UNamur and member of the NaDI Institute, gives us an explanation.

The Namurians of the Year for 2022 are known! Organised by the ASBL "Namurois de l'année" in partnership with the magazine AlluMeuse, the "Namurois de l'année" ceremony has just unveiled the Namur personalities who have distinguished themselves over the past year. And among them, in the science category, we find Anthony Cleve, professor in the Faculty of Computer Science.

The Ten-years Most Influential Paper award has just been presented to three members of UNamur's Faculty of Computer Science: Xavier Devroey, Gilles Perrouin and Maxime Cordy. The award recognizes the paper published ten years previously that has had the greatest impact on the research community. It was awarded at the 18th edition of the International Working Conference on Variability Modelling of Software-Intensive Systems (VAMOS '24), which took place in early February in Bern, Switzerland..

Contact NaDI-CeRCLe Research center for Marketing & Service Management E-mail address Name Question In order to process your request, you must complete all fields marked "optional". When you submit this form, the completed data will be transmitted to UNamur and used to process your request. Learn more about your privacy and your rights Contact and address Prof. Wafa HammediDirectorwafa.hammedi@unamur.be NADI-CeRCLeUniversité de NamurRempart de la Vierge 85000 NamurBelgium Discover the NaDI-CeRCLe research center SVG .cls-1 { fill: #323232; stroke-width: 0px; } Research Excellence See content SVG .cls-1 { fill: #323232; stroke-width: 0px; } Collaborations See content SVG .cls-1 { fill: #323232; stroke-width: 0px; } Impact See content SVG .cls-1 { fill: #323232; stroke-width: 0px; } History See content SVG .cls-1 { fill: #323232; stroke-width: 0px; } Network and community See content SVG .cls-1 { fill: #323232; stroke-width: 0px; } Members See content SVG .cls-1 { fill: #323232; stroke-width: 0px; } Blogs See content