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The lysosome, a small intracellular organelle, is often represented as the stomach of the cell due to its acidity and the presence of numerous digestive enzymes within it. Its role? The degradation of numerous molecules and their recycling to build new molecules and fuel energy production in the cells. Since 2003, Marielle Boonen has been particularly interested in the lysosome. Together with researchers from UNamur, she has highlighted the role of a lysosomal enzyme called HYAL1 in the bone remodelling process.

In the summer of 2022, we set out to discover the qualified researchers of UNamur, winners of the funding granted by the FNRS in 2022. Today, we meet Alison Forrester, currently a post-doctoral researcher at the Institut Curie (Paris) who will join UNamur in September for her new mandate as a FNRS Qualified Researcher within the NARILIS Institute. Her research focuses on the study of compounds that could modify the efficiency of the protein production process and thus envisage new therapeutic approaches.

On 15 March 2023, Prof. Henri-François Renard and Prof. Alison Forrester introduced the new advanced bioimaging tools of the UNamur Morphology & Imaging technology platform available to a broad audience of users.

At UNamur's NARILIS Institute, the 'Stress and AGEing' (SAGE) research group, led by Professor Florence Chainiaux, is seeking to understand the biological processes involved in ageing, focusing on the interconnection between exposure to stress and cellular senescence.

Catherine Michaux, a qualified FNRS researcher, is a partner in the European MSCA-Doctoral Network PROSTAMET project. The special feature of this project is that it funds both research and the training of 9 doctoral students within a network of multidisciplinary experts.

On 13 December 2023, Charlotte Beaudart, a new academic at the University of Namur Faculty of Medicine, will be awarded a prize at the annual ceremony for Belgian scientific research in support of her innovative research on the subject of ageing.

Increasingly sophisticated technologies are invading our spheres of activity without our prior consultation as citizens. Shouldn't the new digital tools, artificial intelligence or technologies resulting from progress in neuroscience, which are transforming our identity and social relationships, be the subject of broad and sufficiently informed democratic debates? This question is at the heart of the international "research-action" project "A new humanism in the age of neuroscience and artificial intelligence" in which UNamur is participating.

In 1996, the European Union created the Marie Skłodowska-Curie Actions (MSCA), a set of prestigious and competitive grants designed to fund research. Thanks to her, the PROSTAMET project got underway on January 1, an ambitious program focused on training PhD students and discovering new therapeutic avenues against prostate cancer, in which UNamur is participating.

The Elongator complex is involved in the addition of 5'-carboxylmethyluridine (cm5U)-derived modifications to transfer RNAs (tRNAs), thereby influencing the translation of certain messenger RNAs (mRNAs) and helping to maintain the integrity of the proteome. This complex is involved in a variety of biological processes, and is of particular importance in oncology. The identification of chemical inhibitors of Elongator is of significant interest in both basic and pharmaceutical research.Through a yeast screen, this work reveals a potential new role for Elongator and identifies a chemical inhibitor of the complex. This compound presents itself as an interesting candidate as a pharmacological inhibitor, opening up new perspectives for the search for anti-cancer therapies.

More info coming soon! More info on the NARILIS website

EMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender). Organisers are encouraged to implement measures to make the meeting environmentally more sustainable.Upon registration - More info and registration on the EMBO website.

Stanford University has published a prestigious ranking that highlights the most influential researchers in a wide range of scientific fields. The list, based on bibliographic criteria, aims to provide a standardized means of identifying the world's scientific leaders. It is one criterion among others for assessing the quality of scientific research. Twelve researchers from the University of Namur are among them!